6202-23-9: Amitriptyline EP Impurity B (HCl salt)
Also known as Cyclobenzaprine HCl or Nortriptyline EP Impurity E, it is a process-related impurity formed during the synthesis of Amitriptyline that is a tricyclic compound that can be effectively utilized as an antimigraine agent.
Additional information on CAS 6202-23-9
3-(5H-Dibenzo[a, d]annulen-5-ylidene)-N, N-dimethylpropan-1-amine hydrochloride
Cyclobenzaprine HCl; Nortriptyline EP Impurity E; 3-(5H-Dibenzo[a, d]cyclohepten-5-ylidene)-N, N-dimethyl-1-propanamine Hydrochloride; Flexeril; Flexiban;Amitriptyline EP Impurity B; Cyclobenzaprine HCl (USP)
Furlanetto, S., et al. “Quality by Design Approach in the Development of a Solvent-Modified Micellar Electrokinetic Chromatography Method: Finding the Design Space for the Determination of Amitriptyline and Its Impurities.” Analytica Chimica Acta, vol. 802, Nov. 2013, pp. 113–24, https://doi.org/10.1016/j.aca.2013.10.005.?
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