399-96-2: Amodiaquine Impurity 4
Amodiaquine Impurity 4 (CAS No: 399-96-2) or 4-Amino-2-fluorophenol is used in the synthesis of 7-Azaindole which is an indole surrogate of growing interest in medicinal chemistry. It has been utilized as an indole bioisostere to develop physicochemical and pharmacokinetic characteristics of various drugs.
Figueroa-Pérez, Santiago, et al. “Efficient Synthesis of 4-O- and C-Substituted-7-Azaindoles.” Tetrahedron Letters, vol. 47, no. 13, Mar. 2006, pp. 2069–72, https://doi.org/10.1016/j.tetlet.2006.01.143.?