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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

73590-06-4Amoxicillin EP Impurity J

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Catalogue No.:	VL1970010
CAS No.:	73590-06-4
Mol. Formula:	C₃₂H₃₈N₆O₁₀S₂
Mol. Weight:	730.81 g/mol

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Additional information on CAS 73590-06-4

Parent drug

Amoxicillin

IUPAC Name

(2R)-(2R)-2-(4-Hydroxyphenyl)glycyl-(2S)-2-[(2R,4S)-4-carboxy-5,5-dimethyl-2-thiazolidinyl]glycyl-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-(4-hydroxyphenyl)glycinamide

Pharmacopoeial Synonyms

Amoxicillin Related Compound J

Other Synonyms

Amoxicillin Dimer; Amoxicillin open ring dimer

Smile

O=C(N)[C@H](C1=CC=C(O)C=C1)N(C(C([C@H]2SC(C)(C)[C@H](C(O)=O)N2)NC(C(C3=CC=C(O)C=C3)N)=O)=O)[C@H]4[C@@]5([H])SC(C)(C)[C@H](C(O)=O)N5C4=O

InChI

InChI=1S/C32H38N6O10S2/c1-31(2)21(29(45)46)36-25(49-31)18(35-24(42)17(33)13-5-9-15(39)10-6-13)26(43)37(19(23(34)41)14-7-11-16(40)12-8-14)20-27(44)38-22(30(47)48)32(3,4)50-28(20)38/h5-12,17-22,25,28,36,39-40H,33H2,1-4H3,(H2,34,41)(H,35,42)(H,45,46)(H,47,48)/t17?,18?,19-,20+,21-,22-,25+,28+/m0/s1

Description

Amoxicillin EP Impurity J known in pharmacopoeias Amoxicillin Related Compound J is a thoroughly characterized reference standard. It meets strict regulatory standards including those set by USP EMA JP and BP. This product is crucial for use in Abbreviated New Drug Applications (ANDA) New Drug Applications (NDA) and the commercial production of Amoxicillin. Additionally it comes with a detailed Structure Elucidation Report (SER) ensuring its precision and dependability for a variety of analytical uses. Amoxicillin EP Impurity J (CAS No: 73590-06-4) or Amoxicillin Dimer is an impurity of Amoxicillin that is an aminopenicillin having an antibacterial activity that is destroyed by gram-positive and gram-negative v-lactamases.

References

Valvo, L., et al. Development of a Simple Liquid Chromatographic Method with UV and Mass Spectrometric Detection for the Separation of Substances Related to Amoxicillin Sodium.â€Â Journal of Chromatography A, vol. 797, no. 1-2, Feb. 1998, pp. 311â€“16, https://doi.org/10.1016/s0021-9673(97)00952-7 Zhu, Yongxin, et al. Evaluation of Liquid Chromatography Methods for the Separation of Ampicillin and Its Related Substances.â€ Journal of Pharmaceutical and Biomedical Analysis, vol. 14, no. 5, Mar. 1996