608141-43-1: Apremilast Impurity 1

Apremilast Impurity 1 (CAS NO.-608141-43-1) IUPAC Name-(S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine acetyl-L-leucinate. Apremilast is an oral phosphodiesterase 4 inhibitor that has an impact on a wide range of inflammatory mediators involved in psoriasis and psoriatic arthritis, this is a novel treatment that focuses on maintaining a balance between pro-inflammatory and anti-inflammatory signals.

Additional information

Catalogue No.

VE008007

CAS No.

608141-43-1

Molecular Formula

C12H19NO4S ; C8H15NO3

Molecular Weight

273.4 ; 173.2 g/mol

IUPAC Name

(S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine acetyl-L-leucinate

References

Schafer, Peter. “Apremilast Mechanism of Action and Application to Psoriasis and Psoriatic Arthritis.” Biochemical Pharmacology, vol. 83, no. 12, June 2012, pp. 1583–90, https://doi.org/10.1016/j.bcp.2012.01.001.

Status

In-stock