Apremilast Impurity 18 (CAS NO.-2055542-18-0) IUPAC Name-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-ol. Apremilast impurirty 18 is an impurity of apremilast. Apremilast is an oral phosphodiesterase 4 inhibitor that has an impact on a wide range of inflammatory mediators involved in psoriasis and psoriatic arthritis, this is a novel treatment that focuses on maintaining a balance between pro-inflammatory and anti-inflammatory signals.
References
Schafer, Peter. “Apremilast Mechanism of Action and Application to Psoriasis and Psoriatic Arthritis.†Biochemical Pharmacology, vol. 83, no. 12, June 2012, pp. 1583–90, https://doi.org/10.1016/j.bcp.2012.01.001.
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