Argatroban Related Compound B is a meticulously characterized reference material that complies with rigorous regulatory requirements, including those defined by USP, EMA, JP, and BP. This product plays a crucial role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Argatroban. It is further supported by a detailed Structure Elucidation Report (SER), ensuring high accuracy and reliability across a broad range of analytical applications. Argatroban Related Compound B (CAS NO-79672-38-1) IUPAC Name-Ethyl (2R,4R)-4-methyl-1-(Nw-nitro-L-arginyl)piperidine-2-carboxylate. Argobatran directly inhibits thrombin by binding to the catalytic site of clot-bound or soluble thrombin molecules. Argatroban, given to patients with heparin-induced thrombocytopenia (HIT) and heparin-induced thrombocytopenia with thrombosis (HITTS), reduced the combined end-point of morbidity and mortality.
References
McKeage, Kate, and Greg L. Plosker. “Argatroban.†Drugs, vol. 61, no. 4, 2001, pp. 515–22, https://doi.org/10.2165/00003495-200161040-00005.
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