Bromfenac Impurity 6, also designated AHR 11652, is a defined brominated aromatic impurity associated with the bromfenac synthetic space and is cataloged under CAS 241825-88-7. With molecular formula C15H8BrNO3 and molecular weight 330.13 g/mol, it represents an oxygenated heteroaromatic species whose origin is consistent with side-reaction chemistry during API preparation or oxidative degradation of related precursors. Its structural features support low-volatility behavior and UV-active chromatographic response. Reliable measurement generally requires high-resolution LC-MS/MS, LC-UV, and, where necessary, orthogonal confirmation by NMR or HRMS to distinguish it from closely related regioisomers and process-related byproducts.
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