Calcitriol EP Impurity B
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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

66791-71-7Calcitriol EP Impurity B

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Catalogue No.:VE006890
CAS No.:66791-71-7
Mol. Formula:C27H44O3
Mol. Weight:416.64g/mol

Additional information on CAS 66791-71-7

Parent drug

Calcitriol

IUPAC Name

(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1β,3β,25-triol

Synonyms

1β-Calcitriol

Description

Calcitriol EP Impurity B, also designated 1β-Calcitriol or 1-epi-Calcitriol, is a stereoisomeric vitamin D3 metabolite with the molecular formula C27H44O3 and molecular weight 416.64 g/mol, CAS 66791-71-7. It differs from calcitriol by inversion at C1, placing the hydroxyl substituent in the β orientation and altering receptor recognition and metabolic behavior. The impurity is typically associated with epimerization during synthesis or storage of secosteroid materials. Because structural confirmation may require separation of closely related epimers, characterization commonly relies on LC-MS/MS, high-resolution MS, and chiral or reversed-phase HPLC with NMR support.

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