Canagliflozin Ring Opening Impurity
Ring-opening product isomer degraded produces under high temperature, Canagliflozin inhibiting the transporter protein SGLT2 in the kidneys, which reduces renal glucose reabsorption.
Additional information on Canagliflozin Ring Opening Impurity
Catalogue No.
VE007523
CAS No.
N/A
Molecular Formula
C24H27FO6S
Molecular Weight
462.53 g/mol
Parent drug
Canagliflozin
IUPAC Name
(2S, 3R, 4R, 5R)-1-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)hexane-1, 2, 3, 4, 5, 6-hexaol
Synonyms
N/A
References
Sci-Hub, Carbohydrate malabsorption mechanism for tumor formation in rats treated with the SGLT2 inhibitor canagliflozin, 10.1016/j.cbi.2014.08.001. (2014). Retrieved December 31, 2021, from Sci-hub.ee website: https://sci-hub.ee/10.1016/j.cbi.2014.08.001
Status
In-stock
