264236-79-5: Celecoxib Carboxylic Acid Acyl-β-D-Glucuronide

Status: In-stock

It is one of impurity present in Celecoxib. Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor, which is a nonsteroidal anti-inflammatory drug, COX-2 is inflamed tissues, and it is induced by inflammatory mediators. inhibition of this enzyme reduces the synthesis of metabolites that include prostaglandin E2, prostacyclin, thromboxane, prostaglandin D2 and prostaglandin F2 inhibition of these mediators leads to the alleviation of pain and inflammation. Celecoxib poses less of an ulceration risk than other NSAIDS, owing to its decreased effect on gastric mucosal prostaglandin synthesis, which is used to treat osteoarthritis, rheumatoid arthritis, acute pain, and menstrual symptoms.

Request quotation

Additional information on CAS 264236-79-5

Catalogue No. VE007714
CAS No. 264236-79-5
Molecular Formula C23H20F3N3O10S
Molecular Weight 587.48 g/mol
Parent drug Celecoxib
IUPAC Name 1-[4-[1-[4-(Aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoate] β-D-glucopyranuronic acid
Synonyms N/A
References Gong, L., Thorn, C. F., Bertagnolli, M. M., Grosser, T., Altman, R. B., & Klein, T. E. (2012). Celecoxib pathways. Pharmacogenetics and Genomics, 22(4), 310–318. https://doi.org/10.1097/fpc.0b013e32834f94cb
Status In-stock

Request a quote

We Respond Within a Few Hours - Whether You're a New or Existing Client

Payment Made Simple: All major Credit/Debit cards accepted

Streamlined 3-Step Process from Quotes to Orders:

Product name:

264236-79-5: Celecoxib Carboxylic Acid Acyl-β-D-Glucuronide

"*" indicates required fields

Hidden
Products quotation
Name
Url
 
Hidden
This field is for validation purposes and should be left unchanged.