301359-05-7: Dantrolene Related Compound A

Dantrolene Related Compound A (CAS No.: 301359-05-7) or 1,2-Bis{[5-(4-nitrophenyl)furan-2-yl]methylene}hydrazine is a metabolite impurity of Dantrolene is indicated for use in chronic disorders characterized by skeletal muscle spasticities like spinal cord injury, stroke, cerebral palsy and multiple sclerosis. Dantrolene is known to work directly on the contractile mechanism of skeletal muscle.

Additional information

Catalogue No.

VE006881

CAS No.

301359-05-7

Molecular Formula

C22H14N4O6

Molecular Weight

430.38

IUPAC Name

1, 2-Bis{[5-(4-nitrophenyl)furan-2-yl]methylene}hydrazine

References

“Development and Application of a Validated Stability-Indicating Ultra-Performance Liquid Chromatography (UPLC) Method for the Determination of Dantrolene and Its Related Impurities.” Clinical Research and Regulatory Affairs, 2021, http://www.tandfonline.com/doi/abs/10.3109/10601331003623309.?Pinder, R. M., et al. “Dantrolene Sodium.” Drugs, vol. 13, no. 1, Jan. 1977, pp. 3–23, https://doi.org/10.2165/00003495-197713010-00002.?

Status

In-stock