Dapagliflozin 5- Member Ring Impurity
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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

1469910-70-0Dapagliflozin 5- Member Ring Impurity

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Catalogue No.:VE006378
CAS No.:1469910-70-0
Mol. Formula:C25H25ClO6
Mol. Weight:408.87 g/mol

Additional information on CAS 1469910-70-0

Parent drug

Dapagliflozin

IUPAC Name

(1S)-1, 4-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol

Pharmacopoeial Synonyms

N/A

Other Synonyms

Dapagliflozin Furanose Isomer; (2S,3R,4R,5S)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-[(1S)-1,2-dihydroxyethyl]oxolane-3,4-diol; (2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-5-((S)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol

Smile

CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@@H](O3)[C@H](CO)O)O)O)Cl

InChI

InChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)20-18(25)19(26)21(28-20)17(24)11-23/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18+,19+,20-,21-/m0/s1

Description

Dapagliflozin 5-Member Ring Impurity, also known Dapagliflozin Furanose Isomer; (2S,3R,4R,5S)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-[(1S)-1,2-dihydroxyethyl]oxolane-3,4-diol is a highly characterized reference material. It fully complies with stringent regulatory standards, including those set by USP, EMA, JP, and BP. This product is essential for use in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Dapagliflozin. Moreover, it comes with a detailed Structure Elucidation Report (SER), ensuring its accuracy and reliability for a wide range of analytical applications. Also known as Dapagliflozin furanose isomer, it was evaluated for use during the study of the Development of New Domino Reactions of Alkylidene Meldrum’s Acids Involving Friedel-Crafts Chemistry and Catalytic Conjugate Allylation of Alkylidene Meldrum’s Acids.

References

‘Dumas, Aaron. Development of New Domino Reactions of Alkylidene Meldrum’s Acids Involving Friedel-Crafts Chemistry and Catalytic Conjugate Allylation of Alkylidene Meldrum’s Acids. uwspace.uwaterloo.ca/bitstream/handle/10012/4784/Dumas_Aaron.pdf?sequence=1&isAllowed=y. Accessed 18 Oct. 2021. ?’

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