1218-69-5: Deferasirox Benzoxazin Impurity

Deferasirox Benzoxazin Impurity (CAS No.: 1218-69-5) or 2-(2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-one is a synthesis intermediate of Deferasirox which is an oral drug iron chelator evaluated for the treatment of transfusional chronic iron overload. The common side effects related to deferasirox treatment are nausea, vomiting, abdominal pain, constipation and diarrhoea and skin rash.

Additional information

Catalogue No.

VE000081

CAS No.

1218-69-5

Molecular Formula

C14H9NO3

Molecular Weight

239.23 g/mol

IUPAC Name

2-(2-Hydroxyphenyl)-4H-1, 3-benzoxazin-4-one

References

Stucky, Stefan, et al. “3, 5-Bis(2-Hydroxyphenyl)-1H-1, 2, 4-Triazole Based Ligands — Protonation and Metal Complex Formation.” Chemical Papers, vol. 62, no. 4, Jan. 2008, https://doi.org/10.2478/s11696-008-0043-x.?Yang, Lily P. H., et al. “Deferasirox.” Drugs, vol. 67, no. 15, 2007, pp. 2211–30, https://doi.org/10.2165/00003495-200767150-00007.?

Status

In-stock