117810-61-4: Desloratadine Related Compound F
Desloratadine Related Compound F (CAS No.: 117810-61-4) or 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxaldehyde is an N-formyl derivative of Desloratadine which is an inhibitor of the human histamine H1 receptor. Desloratadine is attached to membranes expressing the recombinant human histamine H1 receptor and has high potency and 24-h duration of action.
Additional information on CAS 117810-61-4
VL41001
117810-61-4
C20H19ClN2O
338.83
Desloratadine
(8-Chloro-6,11-dihydro-11-(N-formyl-4-piperidinylidene) -5H-benzo[5,6]cyclohepta[1,2-b]pyridine)
O-3-Amino-3-deoxy-?-D-glucopyranosyl-(1?6)-O-[2, 6-diamino-2, 6-dideoxy-?-D-glucopyranosyl-(1?4)]-2-deoxy-D-streptamine; 2'-Amino-2'-deoxykanamycin; Aminodeoxykanamycin; Beckanamycin; Bekanamycin; KDM; Kanendomycin; NK 1006; Nebramycin V; Nebramycin Factor 5; 4-(8-Chloro-5, 6-dihydro-11H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-ylidene)-1-piperidinecarboxaldehyde; Loratadine N-Formyl Impurity
Zheng, Jinjian, and Abu M. Rustum. “Rapid Separation of Desloratadine and Related Compounds in Solid Pharmaceutical Formulation Using Gradient Ion-Pair Chromatography.” Journal of Pharmaceutical and Biomedical Analysis, vol. 51, no. 1, Jan. 2010, pp. 146–52, https://doi.org/10.1016/j.jpba.2009.08.024.?Anthes, John C., et al. “Biochemical Characterization of Desloratadine, a Potent Antagonist of the Human Histamine H1 Receptor.” European Journal of Pharmacology, vol. 449, no. 3, Aug. 2002, pp. 229
In-stock
