117810-61-4: Desloratadine Related Compound F

Status: In-stock

Desloratadine Related Compound F (CAS No.: 117810-61-4) or 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxaldehyde is an N-formyl derivative of Desloratadine which is an inhibitor of the human histamine H1 receptor. Desloratadine is attached to membranes expressing the recombinant human histamine H1 receptor and has high potency and 24-h duration of action.

Additional information on CAS 117810-61-4

Catalogue No. VL41001
CAS No. 117810-61-4
Molecular Formula C20H19ClN2O
Molecular Weight 338.83 g/mol
Parent drug Desloratadine
IUPAC Name (8-Chloro-6,11-dihydro-11-(N-formyl-4-piperidinylidene) -5H-benzo[5,6]cyclohepta[1,2-b]pyridine)
Synonyms O-3-Amino-3-deoxy-?-D-glucopyranosyl-(1?6)-O-[2, 6-diamino-2, 6-dideoxy-?-D-glucopyranosyl-(1?4)]-2-deoxy-D-streptamine; 2'-Amino-2'-deoxykanamycin; Aminodeoxykanamycin; Beckanamycin; Bekanamycin; KDM; Kanendomycin; NK 1006; Nebramycin V; Nebramycin Factor 5; 4-(8-Chloro-5, 6-dihydro-11H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-ylidene)-1-piperidinecarboxaldehyde; Loratadine N-Formyl Impurity
References Zheng, Jinjian, and Abu M. Rustum. “Rapid Separation of Desloratadine and Related Compounds in Solid Pharmaceutical Formulation Using Gradient Ion-Pair Chromatography.” Journal of Pharmaceutical and Biomedical Analysis, vol. 51, no. 1, Jan. 2010, pp. 146–52, https://doi.org/10.1016/j.jpba.2009.08.024.?Anthes, John C., et al. “Biochemical Characterization of Desloratadine, a Potent Antagonist of the Human Histamine H1 Receptor.” European Journal of Pharmacology, vol. 449, no. 3, Aug. 2002, pp. 229
Status In-stock

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117810-61-4: Desloratadine Related Compound F

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