135308-76-8: Desvenlafaxine N,N-Didesmethyl Impurity
Desvenlafaxine N, N-Didesmethyl Impurity (CAS No.: 135308-76-8) or O-Desmethyl-N,N-desmethyl Venlafaxine (HCl salt) is a metabolite of Desvenlafaxine which is a serotonin-norepinephrine reuptake blocker. It is evaluated for use in the treatment of the major depressive disorder (MDD).
O-Desmethyl-N, N-didesmethyl Venlafaxine (HCl salt)
Kumari, Amrita, et al. “Prenatal Desvenlafaxine Induced Behavioural Alterations in Swiss Albino Mice.” Annals of Neurosciences, vol. 21, no. 1, Jan. 2014, https://doi.org/10.5214/ans.0972.7531.210106.?“Efficacy, Safety, and Tolerability of Desvenlafaxine 50 Mg/Day and 100 Mg/Day in Outpatients with Major Depressive Disorder.” Current Medical Research and Opinion, 2021, http://www.tandfonline.com/doi/abs/10.1185/03007990802161923.?