17575-22-3: Digoxin EP mpurity H
Digoxin EP impurity H (CAS No.: 17575-22-3) or Lanatoside C is an FDA-approved cardiac glycoside having an anti-proliferation action on various human cancer cell lines and also is proven to block cell proliferation and inspire apoptosis through attenuating Wnt/β-catenin/c-Myc signaling pathway in the human gastric cancer cell.
(3β, 5β, 12β)-3-[(O-β-D-Glucopyranosyl-(14)-O-3-O-acetyl-2, 6-dideoxy-β-D-ribo-hexopyranosyl-(14)-O-2, 6-dideoxy-β-D-ribo-hexopyranosyl-(14)-2, 6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12, 14-dihydroxycard-20(22)-enolide
Hu, Yudong, et al. “Lanatoside c Inhibits Cell Proliferation and Induces Apoptosis through Attenuating Wnt/v-Catenin/C-Myc Signaling Pathway in Human Gastric Cancer Cell.” Biochemical Pharmacology, vol. 150, Apr. 2018, pp. 280–92, https://doi.org/10.1016/j.bcp.2018.02.023.?