55576-67-5: Digoxin Inhouse Impurity G

Digoxin Inhouse Impurity G (CAS No.: 55576-67-5) or Neo-Digoxin is an adulteration of Digoxin which is a cardiac glycoside and a drug of choice for various heart diseases. Digoxin is extensively evaluated for rate control of atrial fibrillation (AF). However, it has been accompanied by increased mortality.

Additional information

Catalogue No.

VE007267

CAS No.

55576-67-5

Molecular Formula

C43H66O15

Molecular Weight

822.98 g/mol

IUPAC Name

3β-[(2, 6-dideoxy-β-D-arabino-hexopyranosyl-(1→4)-2, 6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2, 6-dideoxy-β-D-ribo- hexopyranosyl)oxy]-12β, 14-dihydroxy-5β-card-20(22)-enolide

Synonyms

Neo-Digoxin

References

Lindenbaum, John, et al. “Inhibition of Digoxin Absorption by Neomycin.” Gastroenterology, vol. 71, no. 3, Sept. 1976, pp. 399–404, https://doi.org/10.1016/s0016-5085(76)80443-x.?Whitbeck, M. G., et al. “Increased Mortality among Patients Taking Digoxin–Analysis from the AFFIRM Study.” European Heart Journal, vol. 34, no. 20, Nov. 2012, pp. 1481–88, https://doi.org/10.1093/eurheartj/ehs348.?

Status

In-stock