Docetaxel EP Impurity A (CAS No.: 1887057-05-7) or 2-Debenzoxyl 2-pentenoyl docetaxel is an adulteration of Docetaxel which is a member of the taxoid class of antineoplastic agents. It depicts its action by bettering the microtubule assembly and by stabilizing microtubules by preventing their depolymerization and thereby disrupting normal cell division.
References
Vasu Dev, R., et al. “Isolation and Characterization of Impurities in Docetaxel.†Journal of Pharmaceutical and Biomedical Analysis, vol. 40, no. 3, Feb. 2006, pp. 614–22, https://doi.org/10.1016/j.jpba.2005.10.037.?Fulton, Bret, and Caroline M. Spencer. “Docetaxel.†Drugs, vol. 51, no. 6, June 1996, pp. 1075–92, https://doi.org/10.2165/00003495-199651060-00011.
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