199734-72-0: Dorzolamide N-Sulfonamide Dimer

Dorzolamide N-Sulfonamide Dimer (CAS No. 199734-72-0) is used in the treatment of open-angle glaucoma. It has two metabolites namely N- Acetyl dorzolamide and N-deethyl-dorzolamide.

Additional information

Catalogue No.

VE006976

CAS No.

199734-72-0

Molecular Formula

C20H29N3O8S6

Molecular Weight

631.85 g/mol

IUPAC Name

(4R, ​6R)​-​rel-4-​(Ethylamino)​-​N-​[[(4S, ​6S)​-​4-​(ethylamino)​-​5, ​6-​dihydro-​6-​methyl-​7, ​7-​dioxido-​4H-​thieno[2, ​3-​b]​thiopyran-​2-​yl]​sulfonyl]​-​5, ​6-​dihydro-​6-​methyl-4H-​thieno[2, ​3-​b]​thiopyran-​2-​sulfonamide-7, 7-dioxide

References

"Hashemi Dehaghi, Mohadeseh, et al. “Dorzolamide Loaded Niosomal Vesicles: Comparison of Passive and Remote Loading Methods.” Iranian Journal of Pharmaceutical Research : IJPR, vol. 16, no. 2, Shaheed Beheshti University of Medical Sciences, 2017, pp. 413–22, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603850/. ?Lo Faro, Alfredo Fabrizio, et al. “Development and Validation of a Fast Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry Method for Determining Carbonic Anhydrase Inhibit

Status

In-stock