105176-70-3: Doxylamine Di-N-Oxide

Doxylamine is a H1 Antagonist. It is prescribed in a combination with pyridoxine for the treatment of nausea and vomitting.

Additional information on CAS 105176-70-3

Catalogue No.

VL38006

CAS No.

105176-70-3

Molecular Formula

C₁₇H₂₂N₂O₃

Molecular Weight

302.37

Parent drug

Doxylamine

IUPAC Name

N, N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-ethanamine N, N’-dioxide

Synonyms

N, N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-ethanamine N, N'-dioxide; N, ?N-?Dimethyl-?2-?[1-?(1-?oxido-?2-?pyridinyl)?-?1-?phenylethoxy]?-?ethanamine N-?oxide

References

"Friedman, H., et al. “Clearance of the Antihistamine Doxylamine.” Clinical Pharmacokinetics, vol. 16, no. 5, May 1989, pp. 312–16, https://doi.org/10.2165/00003088-198916050-00003. ?Koren, Gideon, et al. “Effectiveness of Delayed-Release Doxylamine and Pyridoxine for Nausea and Vomiting of Pregnancy: A Randomized Placebo Controlled Trial.” American Journal of Obstetrics and Gynecology, vol. 203, no. 6, Dec. 2010, pp. 571.e1–7, https://doi.org/10.1016/j.ajog.2010.07.030 "

Status

In-stock

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105176-70-3: Doxylamine Di-N-Oxide

105176-70-3: Doxylamine Di-N-Oxide
Catalogue No.

VL38006

CAS No.

105176-70-3

Molecular Formula

C₁₇H₂₂N₂O₃

Molecular Weight

302.37

Parent drug

Doxylamine

IUPAC Name

N, N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-ethanamine N, N’-dioxide

Synonyms

N, N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-ethanamine N, N'-dioxide; N, ?N-?Dimethyl-?2-?[1-?(1-?oxido-?2-?pyridinyl)?-?1-?phenylethoxy]?-?ethanamine N-?oxide

References

"Friedman, H., et al. “Clearance of the Antihistamine Doxylamine.” Clinical Pharmacokinetics, vol. 16, no. 5, May 1989, pp. 312–16, https://doi.org/10.2165/00003088-198916050-00003. ?Koren, Gideon, et al. “Effectiveness of Delayed-Release Doxylamine and Pyridoxine for Nausea and Vomiting of Pregnancy: A Randomized Placebo Controlled Trial.” American Journal of Obstetrics and Gynecology, vol. 203, no. 6, Dec. 2010, pp. 571.e1–7, https://doi.org/10.1016/j.ajog.2010.07.030 "

Status

In-stock

ListName

Doxylamine Di-N-Oxide

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