Duloxetine Nitroso Impurity (Mixture of Diastereomer)

Duloxetine Nitroso Impurity (Mixture of Diastereomer) Or (S)-N-methyl-N-(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl)nitrous amide. Duloxetine is a potent reuptake inhibitor of serotonin(5-HT) and norepinephrine. It treats depression, diabetic neuropathic pain, anxiety, and fibromyalgia. It is a moderate inhibitor of CYP2D6. It is extensively metabolized by Cytochrome p450.

Additional information

Catalogue No.

VE007668

CAS No.

N/A

Molecular Formula

C18H18N2O2S

Molecular Weight

326.41 g/mol

IUPAC Name

(S)-N-methyl-N-(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl)nitrous amide

References

Carter, Natalie J., and Paul L. McCormack. 'Duloxetine.' CNS Drugs, vol. 23, no. 6, May 2009, pp. 523–41, https://doi.org/10.2165/00023210-200923060-00006. ? Knadler, Mary Pat, et al. 'Duloxetine.' Clinical Pharmacokinetics, vol. 50, no. 5, May 2011, pp. 281–94, https://doi.org/10.2165/11539240-0

Status

In-stock