Efavirenz Related Compound B
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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

440124-96-9Efavirenz Related Compound B

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Catalogue No.:VL1680003
CAS No.:440124-96-9
Mol. Formula:C14H11ClF3NO2
Mol. Weight:317.69 g/mol

Additional information on CAS 440124-96-9

Parent drug

Efavirenz

IUPAC Name

(4S)-6-Chloro-4-[(1E)-2-cyclopropylethenyl]-1, 4-dihydro-4-(trifluoromethyl)-2H-3, 1-Benzoxazin-2-one

Synonyms

Efavirenz IP Impurity B / Efavirenz Ethene Analog / (E)-Dihydro Efavirenz

Description

Efavirenz Related Compound B or Efavirenz IP Impurity B / Efavirenz Ethene Analog / (E)-Dihydro Efavirenz (CAS No.(4S)-6-Chloro-4-[(1E)-2-cyclopropylethenyl]-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-Benzoxazin-2-one. Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that shows inhibitory action against HIV-1. It is a benzoxazinone and orally active compound.

References

‘Adkins, Julie C., and Stuart Noble. “Efavirenz.” Drugs, vol. 56, no. 6, 1998, pp. 1055–64, https://doi.org/10.2165/00003495-199856060-00014. ?Kenedi, Christopher A., and Harold W. Goforth. “A Systematic Review of the Psychiatric Side-Effects of Efavirenz.” AIDS and Behavior, vol. 15, no. 8, Apr. 2011, pp. 1803–18, https://doi.org/10.1007/s10461-011-9939-5 ‘

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