1620758-32-8: Empagliflozin Furanose

Empagliflozin Furanose (CAS No.1620758-32-8) or Mixture of (1R)-1,4-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol and (1S)-1,4-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol. Empagliflozin is a potent, highly selective, sodium-glucose cotransporter-2(SGLT-2) inhibitor. It is well-tolerated antihyperglycemic for the treatment of type-2 diabetes. It reduces renal reabsorption of glucose.

Additional information

Catalogue No.

VE006512

CAS No.

1620758-32-8

Molecular Formula

C23H27ClO7

Molecular Weight

450.91

IUPAC Name

Mixture of (1R)-1, 4-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol and (1S)-1, 4-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol

References

'Wanner, Christoph, et al. “Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes.” New England Journal of Medicine, vol. 375, no. 4, July 2016, pp. 323–34, https://doi.org/10.1056/nejmoa1515920. ?Frampton, James E. “Empagliflozin: A Review in Type 2 Diabetes.” Drugs, vol. 78, no. 10, June 2018, pp. 1037–48, https://doi.org/10.1007/s40265-018-0937-z.'

Status

In-stock