2452301-30-1: Empagliflozin Ortho Isomer

Empagliflozin Ortho Isomer (CAS No.2452301-30-1) or (2S,3R,4R,5S,6R)-2-(4-chloro-3-(2-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Empagliflozin is a potent, highly selective, sodium-glucose cotransporter-2(SGLT-2) inhibitor. It is a well-tolerated antihyperglycemic for the treatment of type-2 diabetes. It reduces renal reabsorption of glucose.

Additional information

Catalogue No.

VE006992

CAS No.

2452301-30-1

Molecular Formula

C23H27ClO7

Molecular Weight

450.9 g/mol

IUPAC Name

(2S, 3R, 4R, 5S, 6R)-2-(4-chloro-3-(2-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3, 4, 5-triol

References

"Frampton, James E. “Empagliflozin: A Review in Type 2 Diabetes.” Drugs, vol. 78, no. 10, June 2018, pp. 1037–48, https://doi.org/10.1007/s40265-018-0937-z. ?Wanner, Christoph, et al. “Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes.” New England Journal of Medicine, vol. 375, no. 4, July 2016, pp. 323–34, https://doi.org/10.1056/nejmoa1515920. ?"

Status

In-stock