76420-74-1: Enalapril EP Impurity A

Enalapril EP Impurity A or (R,S,S)-Enalapril HCl / Enalapril HCl (1R)-Isomer (CAS No.76420-74-1) or (S)-1-((S)-2-(((R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)pyrrolidine-2-carboxylic acid hydrochloride. Enalapril is a prodrug that is hydrolyzed after absorption to form the active angiotensin-converting enzyme Enalaprilat. It is administered orally. It decreases blood pressure by lowering peripheral resistance without increasing heart rate. It is well tolerated and safe.

Additional information

Catalogue No.

VL1360001

CAS No.

76420-74-1

Molecular Formula

C20H27NO5

Molecular Weight

412.91

IUPAC Name

(S)-1-((S)-2-(((R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)pyrrolidine-2-carboxylic acid hydrochloride

Synonyms

(R, S, S)-Enalapril HCl / Enalapril HCl (1R)-Isomer

References

"Todd, Peter A., and Karen L. Goa. “Enalapril.” Drugs, vol. 43, no. 3, Mar. 1992, pp. 346–81, https://doi.org/10.2165/00003495-199243030-00005. ?Davies, Richard O., et al. “Enalapril Worldwide Experience.” The American Journal of Medicine, vol. 77, no. 2, Aug. 1984, pp. 23–35, https://doi.org/10.1016/s0002-9343(84)80055-8. ?"

Status

In-stock