1062122-63-7: Everolimus EP Impurity B

1062122-63-7: Everolimus EP Impurity B

Everolimus EP Impurity B (CAS No: 1062122-63-7) Or (2S)-1-[[(2R,3R,6S)-2-Hydroxy-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19Z,21R)-14- hydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11, 15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaen-1-yl]-3-methyltetrahydro-2H-pyran-2-yl](oxo)acetyl]piperidine-2-carboxylic acid,it is an impurity of Everolimus,Everolimus is derivative of sirolimus,which is inhibitory activity on mTOR,used as immunosuppressant to preven

Additional information on CAS 1062122-63-7

Catalogue No.

VE008464
CAS No.

1062122-63-7
Molecular Formula

C53H83NO14
Molecular Weight

958.22 g/mol
Parent drug

Everolimus
IUPAC Name

(2S)-1-[[(2R, 3R, 6S)-2-Hydroxy-6-[(2S, 3E, 5E, 7E, 9S, 11R, 13R, 14R, 15E, 17R, 19Z, 21R)-14- hydroxy-22-[(1S, 3R, 4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2, 13-dimethoxy-3, 9, 11, 15, 17, 21-hexamethyl-12, 18-dioxodocosa-3, 5, 7, 15, 19-pentaen-1-yl]-3-methyltetrahydro-2H-pyran-2-yl](oxo)acetyl]piperidine-2-carboxylic acid
Synonyms

Everolimus 19-Ene Open-Ring Impurity/ seco Everolimus
References

Sci-Hub, Evaluation of a LC–MS method for everolimus preclinical determination in brain by using [13C2D4]RAD001 internal standard, 10.1016/j.jchromb.2015.01.035. (2015). Retrieved January 20, 2022, from Sci-hub.ee website: https://sci-hub.ee/10.1016/j.jchromb.2015.01.035
Status

In-stock

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1062122-63-7: Everolimus EP Impurity B

1062122-63-7: Everolimus EP Impurity B
Catalogue No.

VE008464
CAS No.

1062122-63-7
Molecular Formula

C53H83NO14
Molecular Weight

958.22 g/mol
Parent drug

Everolimus
IUPAC Name

(2S)-1-[[(2R, 3R, 6S)-2-Hydroxy-6-[(2S, 3E, 5E, 7E, 9S, 11R, 13R, 14R, 15E, 17R, 19Z, 21R)-14- hydroxy-22-[(1S, 3R, 4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2, 13-dimethoxy-3, 9, 11, 15, 17, 21-hexamethyl-12, 18-dioxodocosa-3, 5, 7, 15, 19-pentaen-1-yl]-3-methyltetrahydro-2H-pyran-2-yl](oxo)acetyl]piperidine-2-carboxylic acid
Synonyms

Everolimus 19-Ene Open-Ring Impurity/ seco Everolimus
References

Sci-Hub, Evaluation of a LC–MS method for everolimus preclinical determination in brain by using [13C2D4]RAD001 internal standard, 10.1016/j.jchromb.2015.01.035. (2015). Retrieved January 20, 2022, from Sci-hub.ee website: https://sci-hub.ee/10.1016/j.jchromb.2015.01.035
Status

In-stock
ListName

Everolimus EP Impurity B
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