265121-01-5: Fosaprepitant Dibenzyl Ester

Fosaprepitant Dibenzyl Ester (CAS No. 265121-01-5) or [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-phosphonic Acid bis(Phenylmethyl) Ester is an impurity of Fosaprepitant.Fosaprepitant is used together with other medications to prevent nausea and vomiting that may be caused by chemotherapy in adults and children at least 6 months old.

Additional information on CAS 265121-01-5

Catalogue No.

VE008216

CAS No.

265121-01-5

Molecular Formula

C37H34F7N4O6P

Molecular Weight

794.65 g/mol

Parent drug

Fosaprepitant

IUPAC Name

[3-[[(2R, 3S)-2-[(1R)-1-[3, 5-bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2, 5-dihydro-5-oxo-1H-1, 2, 4-triazol-1-yl]-phosphonic Acid bis(Phenylmethyl) Ester

Synonyms

N/A

References

“Sci-Hub, Efficacy and Safety of Single-Dose Fosaprepitant in the Prevention of Chemotherapy-Induced Nausea and Vomiting in Patients Receiving High-Dose Cisplatin: A Multicentre, Randomised, Double-Blind, Placebo-Controlled Phase 3 Trial. Annals of Oncology, 24(4), 1067–1073, 10.1093/Annonc/Mds541.” Hkvisa.net, 2012, sci-hub.hkvisa.net/www.sciencedirect.com/science/article/pii/S0923753419371844.

Status

In-stock