854372-77-3: Itraconazole EP Impurity B
Itraconazole EP Impurity B (CAS No: 854372-77-3) Or 4-[4-[4-[4-[[cis-2-(2,4-Dichlorophenyl)-2-(4H-1,2,4-triazol-4-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(1RS)-1-methylpropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one, it is an impurity of itraconazole. Itraconazole is a triazole analog, with broad spectrum activity against, a number of fungal species including dermatophytes.
Additional information on CAS 854372-77-3
VL680002
854372-77-3
C35H38Cl2N8O4
705.63
Itraconazole
4-[4-[4-[4-[[cis-2-(2, 4-Dichlorophenyl)-2-(4H-1, 2, 4-triazol-4-ylmethyl)-1, 3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(1RS)-1-methylpropyl]-2, 4-dihydro-3H-1, 2, 4-triazol-3-one
Itraconazole N4-Isomer; rel-4-[4-[4-[4-[[(2R, 4S)-2-(2, 4-Dichlorophenyl)-2-(4H-1, 2, 4-triazol-4-ylmethyl)-1, 3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2, 4-dihydro-2-(1-methylpropyl)-3H-1, 2, 4-triazol-3-one; Itraconazole EP Impurity B
Sci-Hub, [Profiles of Drug Substances, Excipients and Related Methodology], Irbesartan (a comprehensive profile), 10.1016/bs.podrm.2020.07.004. (2020). Retrieved December 10, 2021, from Hkvisa.net website: https://sci-hub.hkvisa.net/10.1016/bs.podrm.2020.07.004
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