3970-35-2: Mesalazine EP impurity Q
It is an impurity present in Mesalazine, Mesalazine is an aminosalicylate drug, which is a topical anti-inflammatory effect on colonic epithelial cells Label, Mucosal production of arachidonic acid metabolites, both through the cyclooxygenase pathways, leukotrienes and hydroxyeicosatetraenoic acids are increased in patients with chronic inflammatory bowel disease, mesalazine diminishes inflammation by blocking cyclooxygenase and inhibiting prostaglandin production in the colon. which is used to treat mild to moderate active ulcerative colitis and also to maintain remission once achieved.
Additional information on CAS 3970-35-2
VE006196
3970-35-2
C7H4ClNO4
201.56
Mesalazine
2-Chloro-3-carboxynitrobenzene
2-Chloro-3-nitrobenzoic Acid
Iacucci, M., de Silva, S., & Ghosh, S. (2010). Mesalazine in Inflammatory Bowel Disease: A Trendy Topic Once Again? Canadian Journal of Gastroenterology, 24(2), 127–133. https://doi.org/10.1155/2010/586092
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