Methylprednisolone EP Impurity D (Hyrdrous)
It is an impurity present in Methylprednisolone, Methylprednisolone is a prednisolone derivative glucocorticoid, which inhibits pro-inflammatory signals and promotes anti-inflammatory signals. corticosteroids decreased vasodilation and permeability of capillaries and also decreased leukocyte migration to sites of inflammation. Glucocorticoids inhibit neutrophil apoptosis and emargination they inhibit phospholipase A2, which decreases the formation of arachidonic acid derivatives they inhibit NF-Kappa B and inflammatory transcription factors.
Additional information on Methylprednisolone EP Impurity D (Hyrdrous)
VE000089
N/A
C22H28O4. H2O
374.47 g/mol
Methylprednisolone
(Z/E)-11β, 20-Dihydroxy-6α-methylpregna-1, 4, 17(20)-triene-3, 21-dione hydrate
N/A
Liu, D., Ahmet, A., Ward, L., Krishnamoorthy, P., Mandelcorn, E. D., Leigh, R., … Kim, H. (2013). A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy. Allergy, Asthma & Clinical Immunology, 9(1). https://doi.org/10.1186/1710-1492-9-30
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Other products related to methylprednisolone
Name of Impurity | Catalogue No. | |
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Methylprednisolone Acetate EP Impurity A | VE009231 | View CAS 93963-74-7 |
Methylprednisolone Acetate EP Impurity C | VE009230 | View CAS 58636-50-3 |
Methylprednisolone Acetate EP Impurity F | VE008839 | View |
Methylprednisolone Acetate EP Impurity G | VE008838 | View CAS 1625-11-2 |
Methylprednisolone Acetate EP Impurity K | VE008841 | View CAS 115321-98-7 |
Methylprednisolone EP Impurity B | VE000087 | View |
Methylprednisolone EP Impurity C | VE000088 | View CAS 61919-52-6 |
Methylprednisolone EP Impurity D | VE006429 | View CAS 1338549-02-2 |
Methylprednisolone EP Impurity E | VE000090 | View CAS 229019-44-7 |
Methylprednisolone EP Impurity F | VE000091 | View CAS 1625-39-4 |
Methylprednisolone EP Impurity G | VE000092 | View CAS 93269-35-3 |
Methylprednisolone EP Impurity H | VE000093 | View CAS 18462-27-6 |
Methylprednisolone EP Impurity J | VE008837 | View CAS 53-36-1 |
Methylprednisolone Ethylothopropionate | VE009207 | View CAS 85198-27-2 |
Methylprednisolone Hydrogen Succinate EP Impurity D | VE0010074 | View CAS 119657-85-1 |