1338549-02-2: Methylprednisolone EP Impurity D

It is an impurity present in Methylprednisolone. Methylprednisolone is a prednisolone derivative glucocorticoid, which inhibits pro-inflammatory signals and promotes anti-inflammatory signals. corticosteroids decreased vasodilation and permeability of capillaries and also decreased leukocyte migration to sites of inflammation. Glucocorticoids inhibit neutrophil apoptosis and emargination they inhibit phospholipase A2, which decreases the formation of arachidonic acid derivatives they inhibit NF-Kappa B and inflammatory transcription factors.

Additional information on CAS 1338549-02-2

Catalogue No.

VE006429

CAS No.

1338549-02-2

Molecular Formula

C22H28O4

Molecular Weight

356.46 g/mol

Parent drug

Methylprednisolone

IUPAC Name

(Z/E)-11β, 20-Dihydroxy-6α-methylpregna-1, 4, 17(20)-triene-3, 21-dione

Synonyms

N/A

References

‌Ocejo, A., & Correa, R. (2022, May 22). Methylprednisolone. Retrieved November 5, 2022, from Nih.gov website: https://www.ncbi.nlm.nih.gov/books/NBK544340/

Status

In-stock