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56718-71-9Metoprolol EP Impurity B
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| Catalogue No.: | VL103012 |
|---|---|
| CAS No.: | 56718-71-9 |
| Mol. Formula: | C9H12O2 |
| Mol. Weight: | 152.19 g/mol |
Additional information on CAS 56718-71-9
Parent drug
MetoprololIUPAC Name
4-(2-Methoxyethyl)phenolSynonyms
p-(2-Methoxyethyl)phenol; Metoprolol Impurity I; Metoprolol Impurity B; p-(2-Methoxyethyl)phenol; Metoprolol EP Impurity BDescription
Metoprolol EP Impurity B, CAS 56718-71-9, is a defined process-related impurity associated with the metoprolol synthetic sequence and structural degradation space. With molecular formula C9H12O2 and molecular weight 152.19 g/mol, it corresponds to a low-molecular-mass aromatic ether derivative requiring mass-selective characterization rather than routine UV assessment alone. Its determination typically relies on orthogonal LC-MS/MS, GC-MS, and high-resolution LC-MS methods, often coupled to impurity profiling by reversed-phase chromatography. Within a regulatory context, such impurities are evaluated under pharmacopeial specifications and ICH impurity control principles because their presence may reflect incomplete alkylation, side-reaction chemistry, or cleavage of the aryloxy side chain.Request a Quote
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