Metoprolol Related Compound C (HCl salt)
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1956321-87-1Metoprolol Related Compound C (HCl salt)

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Catalogue No.:VL103003
CAS No.:1956321-87-1
Mol. Formula:C13H19NO3. HCl
Mol. Weight:237.30 36.46 g/mol

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100 mg $129.00
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Additional information on CAS 1956321-87-1

Parent drug

Metoprolol/ Bisoprolol

IUPAC Name

4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzaldehyde hydrochloride

Pharmacopeial Synonyms

Metoprolol EP Impurity C (HCl salt); Bisoprolol EP Impurity L (HCl salt)

Smiles

O=CC1=CC=C(OCC(O)CNC(C)C)C=C1.[H]Cl

InChI

InChI=1S/C13H19NO3.ClH/c1-10(2)14-7-12(16)9-17-13-5-3-11(8-15)4-6-13;/h3-6,8,10,12,14,16H,7,9H2,1-2H3;1H

Shipping Condition

Ambient Temperature

Synonyms

4-(2-Hydroxy-3-(isopropylamino)propoxy)benzaldehyde hydrochloride; 4-[2-hydroxy-3-(propan-2-ylamino)propoxy]benzaldehyde hydrochloride

Other Synonyms

4-(2-Hydroxy-3-(isopropylamino)propoxy)benzaldehyde hydrochloride;4-[2-hydroxy-3-(propan-2-ylamino)propoxy]benzaldehyde hydrochloride

Description

Metoprolol Related Compound C, also designated Metoprolol EP Impurity C and Bisoprolol EP Impurity L, is the hydrochloride salt of 4-(2-hydroxy-3-(isopropylamino)propoxy)benzaldehyde, CAS 1956321-87-1. With formula C13H19NO3.HCl and molecular weight 237.30, 36.46 g/mol, it represents an aldehydic beta-aryloxypropanolamine related substance arising from incomplete side-chain reduction or oxidative interconversion during synthesis and storage of beta-blocker intermediates. Because the carbonyl function can participate in further derivatization, trace-level control is commonly assessed by LC-MS/MS and orthogonal HPLC methods, with LC-HRMS useful for impurity profiling and confirmation of pharmacopeial identity.

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