287930-77-2: Montelukast (3S)-Hydroxy Propanol

Montelukast (3S)-Hydroxy Propanol (CAS No: 287930-77-2) or Montelukast Diol Impurity is an impurity present in montelukast which is used as efficient therapy in pregnant women and is a selective leukotriene receptor antagonist (LTRA) indicated for the maintenance treatment of asthma.

Additional information

Catalogue No.

VE006802

CAS No.

287930-77-2

Molecular Formula

C29H28ClNO2

Molecular Weight

457.99

IUPAC Name

(S)-2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol

Synonyms

Montelukast Diol Impurity

References

REDDY BAPATUA, HANIMI, et al. “A VALIDATED STABILITY INDICATING UPLC METHOD for MONTELUKAST IMPURITIES in MONTELUKAST SODIUM ORAL GRANULES.” International Journal of Pharma and Bio Sciences, vol. 3, no. 1, 2012, pp. 345–55, https://doi.org/https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.643.8647&rep=rep1&type=pdf. ‌Sarkar, Moumita, et al. “Montelukast Use during Pregnancy: A Multicentre, Prospective, Comparative Study of Infant Outcomes.” European Journal of Clinical Pharmacology, vol. 65, no. 12, Aug. 2009, pp. 1259–64, https://doi.org/10.1007/s00228-009-0713-9. ‌

Status

In-stock