918972-54-0: Montelukast EP Impurity B
Montelukast EP Impurity B (CAS No: 918972-54-0) or Montelukast USP Related Compound F is an impurity present in montelukast which could decrease inflammatory reactions mediated by leukotrienes, lower blood pressure, and also be used to treat asthma.
Additional information on CAS 918972-54-0
VL510003
918972-54-0
C₃₅H₃₄ClNO₂S
568.17
Montelukast
[1-[[[(1R)-1-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(prop-1-en-2-yl)phenyl]propyl]sulfanyl]methyl]cyclopropyl]acetic acid
Montelukast USP Related Compound F; Montelukast Methylstyrene; 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-methylethenyl)phenyl]propyl]thio]methyl]cyclopropaneacetic Acid; Montelukast Impurity; Montelukast EP Impurity B; Montelukast USP Related Compound F; Montelukast Methylstyrene; Styrene Montelukast
CC(=C)C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)O
“New and Practical Synthesis of Montelukast Sodium, an Antiasthmatic Drug.” Synthetic Communications, 2013, http://www.tandfonline.com/doi/abs/10.1080/00397911.2012.684755. ?Nayak, Anjuli, and Ronald B. Langdon. “Montelukast in the Treatment of Allergic Rhinitis.” Drugs, vol. 67, no. 6, 2007, pp. 887–901, https://doi.org/10.2165/00003495-200767060-00005. ?
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