N-Nitroso Pantoprazole

It is one of impurity present in Pantoprazole, Pantoprazole is a proton-pump inhibitor, Pantoprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme at the secretory surface of the gastric parietal cell. As the binding of pantoprazole to the (H+, K+)-ATPase enzyme is irreversible and a new enzyme needs to be expressed to resume acid secretion, pantoprazole’s duration of antisecretory effect. which is used to treat erosive esophagitis and gastric acid hypersecretion, and to promote the healing of tissue damage caused by gastric acid.

Additional information

Catalogue No.

VE0010076

CAS No.

N/A

Molecular Formula

C16H14F2N4O5S

Molecular Weight

412.37 g/mol

Status

In-stock

References

Bernshteyn, M. A., & Masood, U. (2022, July 12). Pantoprazole. Retrieved October 31, 2022, from Nih.gov website: https://www.ncbi.nlm.nih.gov/books/NBK499945/