134720-04-0: N-Nitrosoatenolol

Status: In-stock

It was found to react with sodium nitrite in HC1 solution, yielding the corresponding N-nitrosamines, the genotoxic activity of the six nitrosamines was evaluated in primary cultures of both rat and human hepatocytes.

Additional information on CAS 134720-04-0

Catalogue No. VE007278
CAS No. 134720-04-0
Molecular Formula C14H21N3O4
Molecular Weight 295.33 g/mol
Parent drug Atenolol
IUPAC Name 2-[4-[2-hydroxy-3-(nitroso-propan-2-yl-amino)propoxy]phenyl]acetamide
Synonyms 4-[2-Hydroxy-3-[(1-methylethyl)nitrosoamino]propoxy]benzeneacetamide;
Smiles CC(C)N(CC(COC1=CC=C(C=C1)CC(=O)N)O)N=O
References Robbiano, Luigi, et al. Formation of the, /V-NitrosoDerivatives of Six /?-Adrenergic-Blocking Agents and Their Genotoxic Effects in Rat and Human Hepatocytes1. cancerres.aacrjournals.org/content/canres/51/9/2273.full.pdf. Accessed 21 Oct. 2021.
Status In-stock

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