N Nitrosoatenolol (CAS No: 134720-04-0) was found to react with sodium nitrite in HC1 solution, yielding the corresponding N-nitrosamines, the genotoxic activity of the six nitrosamines was evaluated in primary cultures of both rat and human hepatocytes.
Robbiano, Luigi, et al. Formation of the, /V-NitrosoDerivatives of Six /?-Adrenergic-Blocking Agents and Their Genotoxic Effects in Rat and Human Hepatocytes1. cancerres.aacrjournals.org/content/canres/51/9/2273.full.pdf. Accessed 21 Oct. 2021.