84418-35-9: N-Nitroso Propranolol
It is called a carcinogenic metabolite of propranolol, it is currently recognized as a group of potent chemical carcinogens present in our environment and there is ample in vitro and limited in vivo evidence for nitrosamine formation.
Additional information on CAS 84418-35-9
VE007279
84418-35-9
C16H20N2O3
288.34 g/mol
Atenolol
N-(2-hydroxy-3-(naphthalen-1-yloxy)propyl)-N-isopropylnitrous amide
N/A
CC(C)N(CC(COC1=CC=CC2=CC=CC=C21)O)N=O
Alizadeh, Taher, and Leyla Allahyari. “Highly-Selective Determination of Carcinogenic Derivative of Propranolol by Using a Carbon Paste Electrode Incorporated with Nano-Sized Propranolol-Imprinted Polymer.” Electrochimica Acta, vol. 111, Nov. 2013, pp. 663–73, https://doi.org/10.1016/j.electacta.2013.08.075.?G. Subba Rao. “N-Nitrosamines from Drug and Nitrite: Potential Source of Chemical Carcinogens in Humans? Pharm. Inter. 1:…” ResearchGate, unknown, 1980, http://www.researchgate.net/publication/2792
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