2743-90-0: Nicotine Related Compound A

Also known as (+/-)-Anatabine or Anatabine Racemate, it is an impurity present in Nicotine that accelerates the growth of tumor and atheroma in association with increased neovascularization, enhances endothelial cell growth and tube formation in vitro, and stimulated fibrovascular growth in vivo.

Additional information on CAS 2743-90-0

Catalogue No.

VE008039

CAS No.

2743-90-0

Molecular Formula

C10H12N2

Molecular Weight

160.22 g/mol

Parent drug

Nicotine

IUPAC Name

1, 2, 3, 6-tetrahydro-2, 3'-bipyridine

Synonyms

Anatabine Racemate; (+/-)-Anatabine

References

Denton, Travis T., et al. “Nicotine-Related Alkaloids and Metabolites as Inhibitors of Human Cytochrome P-450 2A6.” Biochemical Pharmacology, vol. 67, no. 4, Feb. 2004, pp. 751–56, https://doi.org/10.1016/j.bcp.2003.10.022.?Heeschen, Christopher, et al. “Nicotine Stimulates Angiogenesis and Promotes Tumor Growth and Atherosclerosis.” Nature Medicine, vol. 7, no. 7, July 2001, pp. 833–39, https://doi.org/10.1038/89961.?

Status

In-stock