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Norfloxacin EP Impurity K
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Documentation

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

70459-07-3Norfloxacin EP Impurity K

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Catalogue No.:VL3030001
CAS No.:70459-07-3
Mol. Formula:C15H16FN3O3
Mol. Weight:305.3 g/mol

Additional information on CAS 70459-07-3

Parent drug

Norfloxacin

IUPAC Name

6-Fluoro-1, 4-dihydro-1-methyl-4-Oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid

Pharmacopoeial Synonyms

Norfloxacin Related Compound K

Other Synonyms

6-fluoro-1-methyl-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid; Norfloxacin N-Methyl Analog

Smiles

O=C(C1=CN(C)C2=C(C=C(F)C(N3CCNCC3)=C2)C1=O)O

Inchl

InChI=1S/C15H16FN3O3/c1-18-8-10(15(21)22)14(20)9-6-11(16)13(7-12(9)18)19-4-2-17-3-5-19/h6-8,17H,2-5H2,1H3,(H,21,22)

Description

Norfloxacin EP Impurity K (CAS No: 70459-07-3) or Norfloxacin N-Methyl Analog is an impurity present in Norfloxacin which is one of the new 4-quinolone antibacterial agents, a fluorinated piperazinyl-substituted congener of nalidixic acid, it demonstrates a much wider in vitro antibacterial spectrum and greater potency than the parent compound.

References

Nageswara Rao, R., and V. Nagaraju. “Separation and Determination of Synthetic Impurities of Norfloxacin by Reversed-Phase High Performance Liquid Chromatography.” Journal of Pharmaceutical and Biomedical Analysis, vol. 34, no. 5, Mar. 2004, pp. 1049–56, https://doi.org/10.1016/j.jpba.2003.11.009.?

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