55453-87-7: Olopatadine Related Compund C
Also known as Isoxepac, is an impurity present in Olopatadine which is currently being developed as a new anti-inflammatory agent and is a relatively new selective H1 antagonist that has mast cell stabilizing properties and has been shown to affect the release of TNFa and various cytokines from conjunctival epithelial cells.
Additional information on CAS 55453-87-7
6, 11-Dihydro-11-oxo-dibenz[b, e]oxepin-2-acetic Acid
Isoxepac; 6, 11-Dihydro-11-oxo-dibenz[b, e]oxepin-2-acetic Acid; Artil; 11-Oxo-6, 11-dihydrodibenz[b, e]oxepin-2-acetic Acid; NSC 300907; Olopatadine USP Related Compound C
Bryce, T. A., and J. L. Burrows. “Quantitative Analysis of 6, 11-Dihydro-11-Oxo-Dibenz[B, E] Oxepin-2-Acetic Acid (Isoxepac) in Plasma and Urine by Gas-Liquid Chromatography.” Journal of Chromatography B: Biomedical Sciences and Applications, vol. 145, no. 3, May 1978, pp. 393–400, https://doi.org/10.1016/s0378-4347(00)81368-7.? McGill, James. “A Review of the Use of Olopatadine in Allergic Conjunctivitis.” International Ophthalmology, vol. 25, no. 3, Springer Science+Business Media, May 2004, pp. 171–79, https://doi.org/10.1007/s10792-004-1818-x. Accessed 26 Oct. 2023.
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