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2374-03-0Oxybuprocaine Hydrochloride EP Impurity C
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| Catalogue No.: | VE0021763 |
|---|---|
| CAS No.: | 2374-03-0 |
| Mol. Formula: | C7H7NO3 |
| Mol. Weight: | 153.14 g/mol |
Additional information on CAS 2374-03-0
Parent drug
OxybuprocaineIUPAC Name
4-Amino-3-hydroxybenzoic AcidPharmacopeial Synonyms
N/ASynonyms
3-hydroxy-4-aminobenzoic acid; (4-Carboxy-2-hydroxyphenyl)amine; 3-Hydroxy-PABA; 3-Hydroxy-p-aminobenzoic acidSmiles
O=C(O)C1=CC=C(N)C(O)=C1InChI
InChI=1S/C7H7NO3/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,9H,8H2,(H,10,11)Shipping Condition
Ambient TemperatureDescription
Oxybuprocaine Hydrochloride EP Impurity C (CAS 2374-03-0), chemically 3-hydroxy-4-aminobenzoic acid or 3-Hydroxy-PABA, is a polar aromatic degradation product and synthetic by-product that requires targeted control in pharmaceutical quality systems. Its ionizable carboxyl and amino groups produce distinct chromatographic behavior, typically eluting early in reversed-phase HPLC and showing a characteristic [M-H] ion by LC-MS. Reliable identification and quantification rely on orthogonal techniques such as LC-MS, proton NMR and IR spectroscopy combined with validated sample preparation to address matrix effects. Monitoring this impurity is essential for EP compliance, impurity profiling, stability assessment and analytical method validation.Request a Quote
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