Additional information on Rifabutin Imine Analogue
Parent drug
Rifabutin
IUPAC Name
Rifabutin Imine Analogue
Synonyms
N/A
Description
Rifabutin Imine Analogue is an antibiotic that prevents sensitive cells from producing DNA-dependent RNA polymerase. In particular, it interacts with bacterial RNA polymerase but does not prevent human RNA polymerase from functioning. It is bactericidal and particularly effective against Mycobacterium TB as well as the majority of gram-positive and gram-negative pathogens, including Pseudomonas aeruginosa. Use is only permitted for the treatment of mycobacterial infections and a few other purposes due to the rapid evolution of resistant microorganisms. When taken orally, rifabutin is effectively absorbed and broadly disseminated throughout body fluids and tissues, including the CSF. Although dose changes are not essential in cases of renal failure, it is processed in the liver and excreted in bile and, to a much lesser amount, in urine.
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To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Always active
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.