Rifabutin Imine Analogue
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  • New Jersey, USA
  • Czech Republic, EU
  • Mumbai, India

* Stock subject to availability.

Documentation

Download MSDS

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

Rifabutin Imine Analogue

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Catalogue No.:VE008622
CAS No.:N/A
Mol. Formula:C46H63N5O10
Mol. Weight:846.02 g/mol

Additional information on Rifabutin Imine Analogue

Parent drug

Rifabutin

IUPAC Name

Rifabutin Imine Analogue

Synonyms

N/A

Description

Rifabutin Imine Analogue is an antibiotic that prevents sensitive cells from producing DNA-dependent RNA polymerase. In particular, it interacts with bacterial RNA polymerase but does not prevent human RNA polymerase from functioning. It is bactericidal and particularly effective against Mycobacterium TB as well as the majority of gram-positive and gram-negative pathogens, including Pseudomonas aeruginosa. Use is only permitted for the treatment of mycobacterial infections and a few other purposes due to the rapid evolution of resistant microorganisms. When taken orally, rifabutin is effectively absorbed and broadly disseminated throughout body fluids and tissues, including the CSF. Although dose changes are not essential in cases of renal failure, it is processed in the liver and excreted in bile and, to a much lesser amount, in urine.

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