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1444772-08-0Rosuvastatin Z-Isomer (Calcium Salt)

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Catalogue No.:	VE006593
CAS No.:	1444772-08-0
Mol. Formula:	C22H27FN3O6S . 1/2 Ca
Mol. Weight:	500.57

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Additional information on CAS 1444772-08-0

Parent drug

Rosuvastatin

IUPAC Name

(3R, 5S, 6Z)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl)amino]-5-pyrimidinyl]-3, 5-dihydroxy- 6-heptenoic acid calcium salt

Pharmacopoeial Synonyms

N/A

Other Synonyms

Calcium (3R,5S,Z)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate

Smile

CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C.CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C.[Ca+2]

InChI

InChI=1S/2C22H28FN3O6S.Ca/c2*1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;/h2*5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30);/q;;+2/p-2/b2*10-9-;/t2*16-,17-;/m11./s1

Decription

Rosuvastatin Z-Isomer (Calcium Salt), also known as Calcium (3R,5S,Z)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate, is a highly characterized reference material. It fully complies with stringent regulatory standards, including those set by USP, EMA, JP, and BP. This product is essential for use in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Rosuvastatin. Moreover, it comes with a detailed Structure Elucidation Report (SER), ensuring its accuracy and reliability for a wide range of analytical applications. It is an isomer of Rosuvastatin. Rosuvastatin belongs to a category of medicines to refer to as statins. It’s used to lower cholesterol.

Description

References

Patil, Premchand, et al. â€œA NOVEL SYNTHESIS APPROACH of ROSUVASTATIN and THEIR INTERMEDIATES.â€ Chaudhari et Al. World Journal of Pharmaceutical Research, vol. 4, 2015, wjpr.s3.ap-south-1.amazonaws.com/article_issue/1443606533.pdf.