Torasemide Nitroso Impurity 1

Torasemide Nitroso Impurity 1 is an impurity present in torasemide, torsemide causes excretion of sodium chloride and water by inhibiting sodium and chloride reabsorption, also have an effect in the renin-angiotensin-aldosterone system by inhibiting the downstream cascade after the activation of angiotensin II, torsemide is prescribed for the treatment of symptomatic heart failure.

Additional information

Catalogue No.

VE009746

CAS No.

N/A

Molecular Formula

C16H19N5O4S

Molecular Weight

377.4 g/mol

IUPAC Name

N-(Isopropylcarbamoyl)-4-(nitroso(m-tolyl)amino)pyridine-3-sulfonamide

References

Mentz, R. J., Buggey, J., Fiuzat, M., Ersbøll, M. K., Schulte, P. J., DeVore, A. D., … Velazquez, E. J. (2015). Torsemide Versus Furosemide in Heart Failure Patients. Journal of Cardiovascular Pharmacology, 65(5), 438–443. https://doi.org/10.1097/fjc.0000000000000212

Status

In-stock