Torasemide Nitroso Impurity 1
Torasemide Nitroso Impurity 1 is an impurity present in torasemide, torsemide causes excretion of sodium chloride and water by inhibiting sodium and chloride reabsorption, also have an effect in the renin-angiotensin-aldosterone system by inhibiting the downstream cascade after the activation of angiotensin II, torsemide is prescribed for the treatment of symptomatic heart failure.
Additional information on Torasemide Nitroso Impurity 1
Mentz, R. J., Buggey, J., Fiuzat, M., Ersbøll, M. K., Schulte, P. J., DeVore, A. D., … Velazquez, E. J. (2015). Torsemide Versus Furosemide in Heart Failure Patients. Journal of Cardiovascular Pharmacology, 65(5), 438–443. https://doi.org/10.1097/fjc.0000000000000212
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