147441-56-3: Tramadol N-Oxide Impurity

It is an impurity present in Tramadol, Tramadol is a centrally acting synthetic opioid analgesic and norepinephrine reuptake inhibitor, tramadol produces respiratory depression by direct action on brain stem respiratory centers, respiratory depression causing the reduction in the responsiveness of the brain stem centers to increase in CO2 tension and to electrical stimulation. depresses the cough reflex with a direct effect on the cough center in the medulla, and also causes a reduction in motility associated with an increase in smooth muscle tone. which is used for moderate to severe pain in adults.

Additional information on CAS 147441-56-3

Catalogue No.

VE006329

CAS No.

147441-56-3

Molecular Formula

C16H25NO3

Molecular Weight

279.37 g/mol

Parent drug

Tramadol

IUPAC Name

(1R, 2R)-rel-2-[(Dimethyloxidoamino)methyl]-1-(3-methoxyphenyl)-cyclohexanol

Synonyms

N/A

References

Sci-Hub, An overview of tramadol and its usage in pain management and future perspective. Biomedicine & Pharmacotherapy, 111, 443–451, 10.1016/j.biopha.2018.12.085. (2018). Retrieved November 4, 2022, from Sci-hub.se website: https://sci-hub.se/https://doi.org/10.1016/j.biopha.2018.12.085

Status

In-stock