124643-35-2Abiraterone Related Compound 2 (Prasterone Triflate)
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| カタログ番号: | VL830009 |
|---|---|
| CAS番号: | 124643-35-2 |
| 分子式: | C20H27F3O4S |
| 分子量: | 420.49 g/mol |
に関する追加情報 CAS 124643-35-2
親薬物
AbirateroneIUPAC名
(3S, 8R, 9S, 10R, 13S, 14S)-3-hydroxy-10, 13-dimethyl-2, 3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl trifluoromethanesulfonate薬局方同義語
N/AOther Synonyms
3β-Hydroxyandrosta-5,16-diene-17-yl trifluoromethanesulfonateSMILES
O=S(C(F)(F)F)(OC1=CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=OInChI
InChI=1S/C20H27F3O4S/c1-18-9-7-13(24)11-12(18)3-4-14-15-5-6-17(19(15,2)10-8-16(14)18)27-28(25,26)20(21,22)23/h3,6,13-16,24H,4-5,7-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1説明
Abiraterone Related Compound 2 (Prasterone Triflate) is a meticulously characterized reference material that complies with rigorous regulatory requirements, including those defined by USP, EMA, JP, and BP. This product plays a crucial role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Abiraterone. It is further supported by a detailed Structure Elucidation Report (SER), ensuring high accuracy and reliability across a broad range of analytical applications. Abiraterone Related Compound 2 (Prasterone Triflate) is a steroidal compound with antiandrogen activity. Abiraterone is used to treat metastatic, castration-resistant prostate cancer mainly in patients who have undergone chemotherapy. Abiraterone acetate is a prodrug of aberaterone.
References
Works Cited de Bono, Johann S., et al. “Abiraterone and Increased Survival in Metastatic Prostate Cancer.†New England Journal of Medicine, vol. 364, no. 21, 26 May 2011, pp. 1995–2005, 10.1056/nejmoa1014618.見積もり依頼
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