Abiraterone Related Compound 2 (Prasterone Triflate)
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内容: HPLC、MASS/LC-MS、1H NMR、FT-IR、含量、構造解析レポート(SER)、および製品に応じた追加分析データ。

124643-35-2Abiraterone Related Compound 2 (Prasterone Triflate)

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カタログ番号:VL830009
CAS番号:124643-35-2
分子式:C20H27F3O4S
分子量:420.49 g/mol

に関する追加情報 CAS 124643-35-2

親薬物

Abiraterone

IUPAC名

(3S, 8R, 9S, 10R, 13S, 14S)-3-hydroxy-10, 13-dimethyl-2, 3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl trifluoromethanesulfonate

薬局方同義語

N/A

Other Synonyms

3β-Hydroxyandrosta-5,16-diene-17-yl trifluoromethanesulfonate

SMILES

O=S(C(F)(F)F)(OC1=CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O

InChI

InChI=1S/C20H27F3O4S/c1-18-9-7-13(24)11-12(18)3-4-14-15-5-6-17(19(15,2)10-8-16(14)18)27-28(25,26)20(21,22)23/h3,6,13-16,24H,4-5,7-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1

説明

Abiraterone Related Compound 2 (Prasterone Triflate) is a meticulously characterized reference material that complies with rigorous regulatory requirements, including those defined by USP, EMA, JP, and BP. This product plays a crucial role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Abiraterone. It is further supported by a detailed Structure Elucidation Report (SER), ensuring high accuracy and reliability across a broad range of analytical applications. Abiraterone Related Compound 2 (Prasterone Triflate) is a steroidal compound with antiandrogen activity. Abiraterone is used to treat metastatic, castration-resistant prostate cancer mainly in patients who have undergone chemotherapy. Abiraterone acetate is a prodrug of aberaterone.

References

Works Cited de Bono, Johann S., et al. “Abiraterone and Increased Survival in Metastatic Prostate Cancer.” New England Journal of Medicine, vol. 364, no. 21, 26 May 2011, pp. 1995–2005, 10.1056/nejmoa1014618.

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