Allopurinol EP Impurity B also known in pharmacopoeias as Allopurinol Related Compound B is a thoroughly characterized reference standard. It meets strict regulatory standards including those set by USP EMA JP and BP. This product is crucial for use in Abbreviated New Drug Applications (ANDA) New Drug Applications (NDA) and the commercial production of Acyclovir . Additionally it comes with a detailed Structure Elucidation Report (SER) ensuring its precision and dependability for a variety of analytical uses. Allopurinol EP Impurity B (CAS No: 22407-20-1) or Allopurinol Related Compound B/5-(formylamino)-1H-pyrazole-4-carboxamide is an impurity formed during the synthesis of Allopurinol that is an oxypurine base used as a first-choice drug in the management of primary and secondary hyperuricemia.
References
Murrell, G. A. C., and W. G. Rapeport. “Clinical Pharmacokinetics of Allopurinol.â€Â Clinical Pharmacokinetics, vol. 11, no. 5, 1986, pp. 343–53, https://doi.org/10.2165/00003088-198611050-00001. Osabe, Makoto, et al. “In Silico Analysis of Interactions between HLA-B*58:01 and Allopurinol-Related Compounds.†Chem-Bio Informatics Journal, vol. 16, no. 0, 2016, pp. 1–4, https://doi.org/10.1273/cbij.16.1. ‌
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