Eltrombopag Impurity 15(CAS 376592-58-4)는 저분자 트롬보포이에틴 수용체 작용제인 엘트롬보팍의 규정된 관련 물질로, 분자식은 C13H8ClNO5이고 분자량은 293.66 g/mol이다. 이 구조는 단순한 염 형태가 아니라 염소 치환을 가진 고도로 산소화된 방향족 분해 산물 또는 합성 중간체 유래 불순물에 부합한다. 이러한 종은 산화 스트레스 조건에서 생성되기 쉽고, 모화합물과의 구조적 유사성으로 인해 분리 거동이 복잡할 수 있다. 따라서 검출과 정량에는 LC-MS/MS, 고해상도 LC-MS, 그리고 정규직 교차 HPLC-UV 방법이 일반적으로 요구된다.
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