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(R)-2,3-dihydroxy-5-(1-hydroxy-2-(methylamino)ethyl)benzenesulfonic acid: Synthesis Attempts and Failure Report
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| 카탈로그 번호: | VE0023116 |
|---|---|
| CAS 번호: | N/A |
온라인 주문
에 대한 추가 정보 (R)-2,3-dihydroxy-5-(1-hydroxy-2-(methylamino)ethyl)benzenesulfonic acid: Synthesis Attempts and Failure Report
Report Format
Delivered in digital PDF format. Printed copies available on request (additional shipping and handling charges apply).Report Language
English by default. Certified translations available at extra cost via our third-party translation partner.설명
(R)-2,3-dihydroxy-5-(1-hydroxy-2-(methylamino)ethyl)benzenesulfonic acid is a chiral, sulfonated aromatic compound featuring a catechol (ortho-dihydroxybenzene) core substituted with a side chain containing a secondary methylamino group and a hydroxyl group.
EMA Guidance on Nitrosamines
According to EMA guidelines, if repeated synthesis attempts fail to detect the formation of nitrosamine impurities, it is likely that the impurity either does not exist or poses an extremely low risk.
Nitrosation
We conducted multiple nitrosation assays under rigorous forced conditions (NAP tests), to evaluate the risk of (R)-2,3-dihydroxy-5-(1-hydroxy-2-(methylamino)ethyl)benzenesulfonic acid formation. Our findings revealed that (R)-2,3-dihydroxy-5-(1-hydroxy-2-(methylamino)ethyl)benzenesulfonic acid does not readily undergo nitrosation under the expected conditions, significantly reducing concerns about its potential formation.
Request Synthesis Failure Report Quote
Our synthesis failure report provides a detailed account of the findings from our synthesis attempts and rigorous testing, demonstrating the non-formation of the nitroso impurity. It offers a comprehensive overview of the evaluated conditions and the resulting data.
(R)-2,3-dihydroxy-5-(1-hydroxy-2-(methylamino)ethyl)benzenesulfonic acid Technical Information
- Molecular Weight: 263.27 g/mol
- Molecular Formula: C9H13NO6S
- IUPAC Name: (R)-2,3-dihydroxy-5-(1-hydroxy-2-(methylamino)ethyl)benzenesulfonic acid
- CAS Number: N/A
- Synonyms: N/A
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와 관련된 기타 제품 Synthesis Attempts and Failure Report impurities
Synthesis Attempts and Failure Report
Synthesis Attempts and Failure Report
Synthesis Attempts and Failure Report
Synthesis Attempts and Failure Report
Synthesis Attempts and Failure Report
Synthesis Attempts and Failure Report
Synthesis Attempts and Failure Report
Synthesis Attempts and Failure Report
Synthesis Attempts and Failure Report
Synthesis Attempts and Failure Report